The mass spectrometry-proteomics core is equipped to analyze both small molecules such as metabolites, and large molecules such as protein and DNA. There are five separate mass spectrometers which can be used for detecting small molecules. For large molecules, this core utilizes the AB SCIEX Triple TOF 5600. This machine is the only one in all of Texas, and takes macromolecule detection to the next level.
“This machine is 5-fold faster, 10-fold more sensitive than any other mass spec technology available in the medical center, only requiring a Pico-gram worth of sample,” said Eastwood Leung, Ph.D., the director of the core. Mass spectrometry can be used for mass determination, peptide sequencing, protein profiling, identifying post-translational modifications, sub-proteome isolation, and biomarker identification in clinical samples. This exciting new core opened approximately two months ago and is currently accepting new clients. For more information or to make an appointment please contact Eastwood Leung, Ph.D. at 713-798-6360 or Hleung@bcm.edu.